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Related Experiment Video

Updated: Apr 11, 2026

Small Bowel Transplantation In Mice
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Small Bowel Transplantation In Mice

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Belgian multicenter experience with intestinal transplantation.

Laurens J Ceulemans1,2, Diethard Monbaliu1,2, Arnaud De Roover3

  • 1Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.

Transplant International : Official Journal of the European Society for Organ Transplantation
|June 3, 2015
PubMed
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This summary is machine-generated.

Intestinal transplantation (ITx) is a viable treatment for intestinal failure, showing promising survival and quality of life improvements in Belgian patients. This multicenter analysis highlights ITx as a life-saving therapy, restoring nutritional independence and overall well-being.

Area of Science:

  • Gastroenterology
  • Transplantation Surgery
  • Clinical Medicine

Background:

  • Intestinal transplantation (ITx) has advanced from experimental to clinical practice, yet challenges persist.
  • Multicenter data are crucial for understanding the evolving landscape of ITx outcomes.

Purpose of the Study:

  • To analyze the comprehensive multicenter experience with intestinal transplantation in Belgium.
  • To evaluate patient and graft survival rates, indications, and long-term outcomes.

Main Methods:

  • A retrospective analysis of 24 intestinal transplantations performed between 1999 and 2014 across five Belgian centers.
  • Data collected included recipient demographics, indications for ITx, graft types, and post-transplant complications such as rejection and lymphoproliferative disease.
Keywords:
BelgiumEurotransplantintestinal failureintestinal transplantationmultivisceral transplantation

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Related Experiment Videos

Last Updated: Apr 11, 2026

Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

15.2K
Orthotopic Small Bowel Transplantation in Rats
09:16

Orthotopic Small Bowel Transplantation in Rats

Published on: November 6, 2012

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Tissue Engineering of the Intestine in a Murine Model
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Tissue Engineering of the Intestine in a Murine Model

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Main Results:

  • Twenty-three patients (6 children, 17 adults) underwent ITx for various conditions including intestinal ischemia, volvulus, and splanchnic thrombosis.
  • One- and five-year patient survival rates were 71.1% and 62.8%, respectively; graft survival rates were 58.7% and 53.1%.
  • Among long-term survivors (1+ year), 100% achieved nutritional independence and maintained a high quality of life (Karnofsky score >90%), with no renal failure.

Conclusions:

  • Intestinal transplantation in Belgium has matured into a life-saving therapy.
  • ITx offers significant potential for restoring quality of life and achieving nutritional independence in patients with end-stage intestinal failure.