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Updated: Apr 11, 2026
![[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
[3+2] Redox-Neutral Cycloaddition of Nitrocyclopropanes with Styrenes by Visible-Light Photocatalysis
Chengfeng Wang1, Xiang Ren1, Hujun Xie2
1Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang 310028 (P. R. China) http://mypage.zju.edu.cn/lu.
Abstract:
The first nitro-group-initiated redox-neutral [3+2] cycloaddition of nitrocyclopropanes with alkenes by using visible-light-absorbing transition-metal complexes was reported. High diastereoselectivities were observed for two quaternary carbon centers on the ring and validated by DFT calculations. Spiro- or polycyclic structures can be constructed smoothly. Cyclic γ-amino acid derivatives and polysubstituted cyclic amino alcohols can be obtained easily through reduction of the nitro group.
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