Related Experiment Video

Updated: Apr 11, 2026

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats
06:32

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Published on: June 28, 2019

8.6K

Fractional flow reserve-guided management in stable coronary disease and acute myocardial infarction: recent

Colin Berry1, David Corcoran2, Barry Hennigan3

  • 1West of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Clydebank, UK BHF Glasgow Cardiovascular Research Centre, Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK colin.berry@glasgow.ac.uk.

European Heart Journal
|June 4, 2015
PubMed

Insights

Fractional flow reserve (FFR) improves coronary artery disease (CAD) diagnosis and treatment decisions. This review covers recent FFR advancements in stable CAD and myocardial infarction, impacting patient outcomes.

Area of Science:

  • Cardiology
  • Diagnostic Imaging
  • Interventional Cardiology

Background:

  • Coronary artery disease (CAD) poses a significant global health burden.
  • Accurate diagnosis and effective treatment of CAD are crucial for reducing morbidity and mortality.
  • Fractional flow reserve (FFR) is a key diagnostic tool for assessing the physiological significance of coronary stenoses.

Purpose of the Study:

  • To review recent advancements in Fractional Flow Reserve (FFR) applications for Coronary Artery Disease (CAD).
  • To explore novel developments in CAD pathophysiology, diagnostic utility, and prognostic insights related to FFR.
  • To summarize the impact of FFR on revascularization decisions and clinical outcomes in stable CAD and recent myocardial infarction.

Main Methods:

  • Review of recent literature and clinical studies on FFR in CAD.
  • Analysis of FFR's role in stable CAD and recent myocardial infarction management.
  • Examination of FFR's influence on clinical decision-making and patient outcomes.

Main Results:

  • FFR significantly impacts decisions regarding revascularization compared to standard angiography.
  • FFR provides crucial physiological information beyond anatomical stenosis assessment.
  • Recent developments enhance the understanding and application of FFR in diverse CAD patient populations.

Conclusions:

  • FFR is an evidence-based diagnostic test that improves the management of coronary artery disease.
  • Advancements in FFR offer improved diagnostic accuracy and prognostic value.
  • FFR-guided management leads to better clinical outcomes in patients with stable CAD and recent myocardial infarction.

Keywords:
Coronary revascularizationFractional flow reserveMedical therapyMyocardial infarctionStable angina

More Related Videos

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice05:07

Author Spotlight: Improved Localization and Monitoring of Coronary Flow Reserve Using Modified PLAX View in Mice

Published on: August 25, 2023

2.2K
Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice06:39

Ultrasound Based Assessment of Coronary Artery Flow and Coronary Flow Reserve Using the Pressure Overload Model in Mice

Published on: April 13, 2015

15.9K

Related Concept Videos

Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
487
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
439
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
421
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
565
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
567
Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
1.8K