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Updated: Apr 11, 2026

Partial Heterotopic Hindlimb Transplantation Model in Rats
Published on: June 9, 2021
[Severe leg trauma in a resource-poor environment: indications for amputation in emergencies]
J C Murison1, S Rigal1, C D Niang2
1Chirurgie orthopédique et traumatologie, HIA Percy, 101, avenue Henri Barbusse, 92160 Clamart, France.
Abstract:
Although the development of multitissue limb reconstruction has reduced the role of post-traumatic primary amputation of the leg, some patients should nonetheless undergo emergency amputations. In developing countries, the socioeconomic context associated with the limited health care supply compromises still further the prognosis of preservation efforts. The decision criteria for surgery are thus different in these settings. The choice of emergency leg amputation or attempted preservation in developing countries depends on the epidemiology of severe leg trauma, the local and general prognosis, and the practice conditions. Three factors must be combined before limb preservation can be attempted: adequate local and general adequate wound elements, an available, experienced surgeon with a competent care structure, and a favorable social context.
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