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The sum of all browning in FGF21 therapeutics
Paul Lee1, Michael M Swarbrick2, Jerry R Greenfield1
1Diabetes and Metabolism Division, Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia; Department of Endocrinology, St. Vincent's Hospital, Sydney, Darlinghurst, NSW 2010, Australia.
Cell Metabolism
|June 4, 2015
Abstract:
FGF21 mimetics are a promising therapeutic tool, believed to exert their anti-obesity effect partly through browning of white fat. Véniant et al. (2015) and Samms et al. (2015) present evidence arguing against fat browning as the primary mechanism causal to weight loss following FGF21-based treatment in mice.

