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Bone fragility fractures in hemodialysis patients: Croatian surveys

Iva Šimunović, Draško Pavlović, Boris Kudumija

    Collegium Antropologicum
    |June 5, 2015
    PubMed

    Insights

    Bone fractures are common in Croatian hemodialysis patients, with a 4.0% prevalence. Hip fractures were most frequent, highlighting a significant fracture risk in this population.

    Area of Science:

    • Nephrology
    • Orthopedics
    • Metabolic Bone Disease

    Background:

    • Chronic kidney disease (CKD) frequently causes bone mineral metabolism disturbances.
    • Bone fractures are a major complication, impacting patient morbidity and mortality.
    • Understanding fracture prevalence in hemodialysis patients is crucial for risk assessment.

    Purpose of the Study:

    • To determine the prevalence of bone fractures in Croatian hemodialysis patients.
    • To identify potential risk factors associated with fractures in this cohort.
    • To establish baseline epidemiological data for bone fractures in this specific population.

    Main Methods:

    • Retrospective analysis of 767 hemodialysis patients across nine Croatian centers.
    • Data collection included demographics, laboratory results, and fracture history from medical records.
    • Fractures were classified according to World Health Organization criteria for fragility fractures.

    Main Results:

    • A total of 36 fractures were recorded in 31 patients, yielding a prevalence of 4.0%.
    • The mean age of patients with fractures was 68.6 years, with women more affected than men.
    • Hip fractures (39%) and forearm fractures (22%) were the most common types observed.

    Conclusions:

    • The prevalence of bone fractures among Croatian hemodialysis patients is notably high.
    • Older age, female sex, longer duration of hemodialysis, and elevated parathyroid hormone (PTH) levels are associated with increased fracture risk.
    • This study provides essential epidemiological insights into bone fractures within the Croatian hemodialysis population.

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