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Updated: Apr 11, 2026

mirMachine: A One-Stop Shop for Plant miRNA Annotation
Published on: May 1, 2021
Plant developmental transitions: the role of microRNAs and sugars
Sha Yu1, Heng Lian2, Jia-Wei Wang3
1National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Shanghai 200032, People's Republic of China; University of the Chinese Academy of Sciences, Beijing 100049, People's Republic of China.
Abstract:
What determines the rate at which a multicellular organism ages is a mystery in biology. In plants the changes in morphological and physiological traits serve as markers for the developmental transitions. Mutant characterizations and genetic analyses in Arabidopsis thaliana delineate an evolutionarily conserved, microRNA156 (miR156)-guided timing mechanism that temporally regulates many aspects of biological processes during development. Recent studies now reveal that sugar metabolites, the products of photosynthesis, feed into this developmental timer by regulating miR156 levels, thereby ensuring that each developmental transition occurs under favorable conditions.
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