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Updated: Apr 11, 2026

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
Published on: March 26, 2015
Regenerative Medicines for Remyelination: From Aspiration to Reality
1Wellcome Trust-MRC Cambridge Stem Cell Institute, The Clifford Allbutt Building, Cambridge Biomedical Campus, University of Cambridge, Hills Road, Cambridge CB2 0AH, UK.
Abstract:
Stimulating an endogenous regenerative response is a powerful approach for potential treatment of chronic demyelinating diseases such as multiple sclerosis. Recently in Nature, Najm et al. (2015) identified two clinically relevant, FDA-approved compounds that promote oligodendrocyte progenitor cell differentiation and induce remyelination in demyelinating disease models.
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