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Transcription

Transcription

Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...

Euchromatin

Euchromatin

Regulated mRNA Transport

Regulated mRNA Transport

Transfer RNA Synthesis

Transfer RNA Synthesis

tRNA Activation

tRNA Activation

Eukaryotic RNA Polymerases

Eukaryotic RNA Polymerases

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Related Experiment Video

Updated: Apr 11, 2026

mRNA Interactome Capture from Plant Protoplasts

mRNA Interactome Capture from Plant Protoplasts

Published on: July 28, 2017

The Arabidopsis epitranscriptome.

Rupert G Fray¹, Gordon G Simpson²

¹School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leicestershire LE12 5RD, UK.

Current Opinion in Plant Biology

|June 7, 2015

Summary

This summary is machine-generated.

N(6)-methyladenosine (m(6)A) is a key plant RNA modification. Recent studies show m(6)A is crucial for Arabidopsis development, revealing a vital layer of gene regulation.

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Area of Science:

Molecular Biology
Plant Science
Genetics

Background:

N(6)-methyladenosine (m(6)A) is the most prevalent internal modification of plant messenger RNAs.
The epitranscriptome, encompassing mRNA modifications, has gained recent scientific interest.
m(6)A was initially discovered in the 1970s but was largely overlooked until recently.

Purpose of the Study:

To review recent progress in understanding the epitranscriptome.
To highlight the importance of m(6)A in plant gene regulation.
To identify outstanding questions in the field of epitranscriptomics.

Main Methods:

Analysis of existing literature on mRNA modifications.
Review of recent studies mapping m(6)A in Arabidopsis.
Synthesis of current knowledge on the biological impacts of the epitranscriptome.

Main Results:

Thousands of Arabidopsis mRNAs are methylated.
mRNA methylation, specifically m(6)A, is essential for normal plant development.
Arabidopsis serves as a valuable model for studying epitranscriptomic effects.

Conclusions:

The epitranscriptome represents a significant, previously overlooked layer of gene regulation.
Further research in Arabidopsis will be crucial for understanding the broad biological impacts of mRNA modifications.
The study of m(6)A and the epitranscriptome offers new avenues for exploring plant biology.