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Updated: Apr 11, 2026

Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes
Published on: July 19, 2022
Crossover of two power laws in the anomalous diffusion of a two lipid membrane
Evangelos Bakalis1, Siegfried Höfinger1, Alessandro Venturini2
1Dipartimento di Chimica "G. Ciamician", Universita' di Bologna, Via F. Selmi 2, 40126 Bologna, Italy.
Abstract:
Molecular dynamics simulations of a bi-layer membrane made by the same number of 1-palmitoyl-2-oleoyl-glycero-3-phospho-ethanolamine and palmitoyl-oleoyl phosphatidylserine lipids reveal sub-diffusional motion, which presents a crossover between two different power laws. Fractional Brownian motion is the stochastic mechanism that governs the motion in both regimes. The location of the crossover point is justified with simple geometrical arguments and is due to the activation of the mechanism of circumrotation of lipids about each other.
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