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Updated: Apr 11, 2026

Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
PET/MRI in the Upper Abdomen
Maria Gavra1, Rizwan Syed1, Francesco Fraioli1
1Institute of Nuclear Medicine, University College London Hospital NHS Foundation Trust, London, UK.
Abstract:
PET/CT and contrast-enhanced CT have been considered the standard imaging modalities in the diagnosis of upper abdominal malignancies. PET/CT can be challenging in soft tissue delineation, especially in the upper abdomen. The recent development of PET/MRI for clinical use has shown promising results, with MRI providing superior soft tissue contrast and PET providing biochemical and metabolic information. Combined PET/MRI may allow simultaneous benefit in the assessment of patients in a single session, improving patient journey, lesion detectability, diagnostic performance, and prognostic information. PET/MRI also provides the ability for tissue characterization and reduces radiation exposure. The most powerful driver is PET, and the newer PET radiopharmaceuticals with the addition of dynamic contrast-enhanced MRI, diffusion-weighted imaging, and MR spectroscopy may increase the sensitivity and specificity of disease recognition and have clinical effect. In this article, we review the advantages and limitations of PET/MRI in upper abdominal malignancies.
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