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Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
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Human serum biomarker detection based on a cascade signal amplification strategy by a DNA molecule machine
Jing Liu1, Xiaoyan Xin, Hong Zhou
1School of Chemistry and Chemical Engineering of Linyi University, Linyi 276005, P. R. China. shushzhang@126.com.
Chemical Communications (Cambridge, England)
|June 9, 2015
Abstract:
A convenient method is presented that employs a DNA machine for protein biomarker detection. The detection limit is 400 times lower compared to the method without a DNA machine. This study provides a promising method that could realize most protein biomarker detections without the corresponding aptamers, using a DNA machine for signal amplification.
