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Updated: Apr 11, 2026

Radiotracer Administration for High Temporal Resolution Positron Emission Tomography of the Human Brain: Application to FDG-fPET
Published on: October 22, 2019
Fluorodeoxyglucose PET in Neurology and Psychiatry
Michael Schöll1, Andrés Damián2, Henry Engler3
1MedTech West and the Department of Clinical Neuroscience and Rehabilitation, University of Gothenburg, Blå stråket 5, 6th Floor, Gothenburg 413 45, Sweden; Department NVS, Center for Alzheimer Research, Translational Alzheimer Neurobiology, Karolinska Institute, Novum 5th Floor, Stockholm 14186, Sweden.
Abstract:
PET imaging with the most widely available PET tracer, 2-deoxy-2-[(18)F]fluoro-d-glucose (FDG), is a powerful tool in the differential diagnosis of numerous neurologic and psychiatric disorders, particularly in early disease stages. It also plays an important role in the longitudinal evaluation of treatment effects and the depiction of disease courses. A selection of established and eligible application areas of FDG PET in neurology and psychiatry, such as different types of dementia, epilepsy, schizophrenia, and bipolar disorder, are reviewed in this article. A general methodology for clinical FDG PET examinations and typical diagnostic criteria and pitfalls are addressed.
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