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Profound bradycardia associated with NIV removal
C Echevarria1, S C Bourke1, G J Gibson2
1North Tyneside General Hospital, Rake Lane, North Shields, Tyne and Wear, NE29 8NH, United Kingdom.
Respiratory Medicine Case Reports
|June 10, 2015
Summary
A patient with amyotrophic lateral sclerosis (ALS) experienced vasovagal episodes and respiratory failure. Bradycardia occurred upon mask removal during non-invasive ventilation, suggesting a link between ALS progression and autonomic dysfunction.
Area of Science:
- Neurology
- Pulmonology
- Cardiology
Background:
- Amyotrophic lateral sclerosis (ALS) can affect autonomic function.
- Respiratory failure is a common complication of ALS.
- Vasovagal syncope is a potential manifestation of autonomic dysfunction.
Purpose of the Study:
- To describe a case of ALS with unusual autonomic and respiratory complications.
- To explore the potential link between ALS, vasovagal episodes, and bradycardia during non-invasive ventilation.
Main Methods:
- Case report of a patient with lower-limb onset ALS.
- Clinical observation of respiratory failure, vasovagal episodes, and bradycardia.
- Literature review on ALS and autonomic dysfunction.
Main Results:
- The patient presented with respiratory failure and vasovagal episodes.
- Recurrent profound bradycardia occurred upon removal of non-invasive ventilation.
- Symptoms gradually resolved over ten days.
Conclusions:
- The case highlights potential autonomic dysregulation in ALS.
- Bradycardia during mask removal may be related to autonomic responses in ALS patients.
- Further investigation into autonomic dysfunction in ALS is warranted.
Keywords:
Amyotrophic lateral sclerosisBradycardiaHypercapniaMotor Neurone DiseaseNon-invasive ventilationRespiratory failureMore Related Videos
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