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The Ankle-Brachial Index is Associated With Cardiovascular Complications After Noncardiac Surgery
G A Carmo1, D Calderaro1, D M Gualandro1
1Interdisciplinary Medicine in Cardiology Unit, Heart Institute, University of Sao Paulo Medical School, São Paulo, Brazil.
Insights
An abnormal ankle-brachial index (ABI) indicates peripheral artery disease (PAD) and is linked to increased cardiovascular complications following noncardiac surgery. Early detection can improve patient outcomes.
Area of Science:
- Cardiology
- Vascular Medicine
- Perioperative Medicine
Background:
- The ankle-brachial index (ABI) is a non-invasive test assessing peripheral artery disease (PAD).
- Cardiovascular complications are a significant concern in patients undergoing noncardiac surgery.
Purpose of the Study:
- To investigate the association between abnormal ABI and the incidence of cardiovascular events after noncardiac surgery.
- To identify the risk of perioperative cardiovascular complications in patients with PAD.
Main Methods:
- Prospective evaluation of 124 patients undergoing noncardiac surgery.
- ABI measurement pre-surgery; patients with ABI ≤ 0.9 formed the PAD group.
- Follow-up to 30 days for cardiovascular events including death, ACS, ITE, HF, shock, arrhythmias, arrest, edema, stroke, and PAD symptoms.
Main Results:
- Patients with abnormal ABI (PAD group) experienced a significantly higher event rate (57.9%) compared to controls (25.7%, P = .011).
- Isolated troponin elevation (ITE) was the most frequent event (24.2%).
- Logistic regression revealed an odds ratio of 7.4 for ITE in the PAD group (95% CI 2.2-25.0, P = .001).
Conclusions:
- An abnormal ABI is a significant predictor of increased cardiovascular event occurrence in patients undergoing noncardiac surgery.
- The findings highlight the importance of ABI screening in this patient population to identify individuals at higher risk.
Background:
This study evaluated the association of the ankle-brachial index (ABI) and cardiovascular complications after noncardiac surgery.
Methods:
We prospectively evaluated patients referred for noncardiac surgery. The ABI was performed before surgery. Patients with abnormal ABI (≤ 0.9) were included in the peripheral artery disease (PAD) group and the remaining constituted the control group. Cardiac troponin and electrocardiogram were obtained 72 hours after surgery. Patients were followed up to 30 days, and primary end point was the occurrence of any cardiovascular event: cardiovascular death, acute coronary syndrome, isolated troponin elevation (ITE), decompensated heart failure, cardiogenic shock, unstable arrhythmias, nonfatal cardiac arrest, pulmonary edema, stroke, or PAD symptoms increase.
Results:
We evaluated 124 patients (61.3% male; mean age 65.4 years). During the study, 57.9% of patients in the PAD group had an event versus 25.7% in the control group (P = .011). The ITE was the most observed event (24.2%). After logistic regression, the odds ratio for ITE was 7.4 (95% confidence interval 2.2-25.0, P = .001).
Conclusions:
In patients submitted to noncardiac surgery, abnormal ABI is associated with a higher occurrence of a cardiovascular event.
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