Causes of visual impairment in children seen at a university-based hospital low vision service in Brazil

Insights

This study on pediatric visual impairment in Brazil found congenital cataract, toxoplasmosis, and glaucoma as leading causes. A high percentage of cases were preventable, with late diagnosis highlighting a critical public health issue.

Area of Science:

  • Ophthalmology
  • Public Health
  • Epidemiology

Background:

  • Visual impairment significantly impacts child development.
  • Early detection and intervention are crucial for managing pediatric visual impairment.
  • Understanding the epidemiology of visual impairment in children is essential for targeted public health strategies.

Purpose of the Study:

  • To characterize the epidemiologic features of visually impaired children (0-7 years) at a Brazilian university hospital's low vision service.
  • To identify the primary causes and affected ocular regions in pediatric visual impairment.
  • To assess the proportion of avoidable causes and the age at first appointment.

Main Methods:

  • Retrospective review of medical records for 229 visually impaired patients aged 0-7 years.
  • Data collection included sociodemographic factors, ocular disorders, affected anatomic regions, etiology, and cause avoidability.
  • Analysis utilized World Health Organization classifications for etiologies.

Main Results:

  • Congenital cataract (14%), toxoplasmosis (14%), and congenital glaucoma (13%) were the most frequent diagnoses.
  • The retina (18%) and lens (15%) were the most affected anatomic regions; 33% had normal-appearing globes.
  • Undetermined (43%), perinatal/neonatal (22%), and intrauterine (20%) factors were leading etiologies; 64% of cases had avoidable causes.

Conclusions:

  • Congenital cataract, toxoplasmosis, and congenital glaucoma are the primary causes of infant blindness in this cohort.
  • The high percentage of avoidable causes and the late mean age at first appointment underscore significant public health concerns.
  • Targeted interventions and improved access to care are needed to address preventable pediatric visual impairment.
Abstract

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