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Published on: October 25, 2024
A new diagnostic marker for acute pulmonary embolism in emergency department: mean platelet volume
Fahrettin Talay1, Tarık Ocak2, Aytekin Alcelik3
1Department of Chest Diseases, Abant Izzet Baysal Medical Faculty, Bolu, Turkey.
Objective:
To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED).
Methods:
Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient.
Results:
A total of 315 consecutive patients were analyzed, including 150 patients (53.44 ± 15.14 y; 92 men/58 women) in APE group and 165 patients (49.80 ±13.76y; 94 men/71 women) in the control group. MPV in the APE group was significantly higher than in the control group (9.42±1.22 fl vs. 8.04±0.89 fl, p<0.0001). The best cut-off values for MPV when predicting APE in patients with clinically suspected APE presenting at the ED were 8.55 fl (sensitivity 82.2%; specificity 52.3%).
Conclusions:
MPV is a helpful parameter for the diagnosis of APE in ED, for the first time in the literature.
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