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Pyogenic Granuloma of the Sigmoid Colon causing Intussusception in an Infant

Salvatore Garofalo1, Michael Mostert2, Isabella Morra3

  • 1Department of Paediatric Surgery, Regina Margherita Children's Hospital, Italy.

APSP Journal of Case Reports
|June 12, 2015
PubMed

Insights

A rare sigmoid colon pyogenic granuloma caused intussusception in an infant. Surgical removal provided a cure, and progesterone exposure during pregnancy may be a potential cause.

Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Pathology

Background:

  • Pyogenic granuloma is a benign vascular tumor.
  • Gastrointestinal tract involvement is uncommon.
  • Intussusception is a surgical emergency in infants.

Observation:

  • A 4-month-old boy presented with intussusception.
  • The intussusception was caused by a sigmoid colon pyogenic granuloma.
  • The mother reported high-dose progesterone exposure during early pregnancy.

Findings:

  • Surgical resection and anastomosis successfully treated the pyogenic granuloma and intussusception.
  • Progesterone exposure is a potential etiological factor for pyogenic granuloma in this case.

Implications:

  • This case highlights a rare cause of intussusception in infants.
  • Further research may explore the role of hormonal factors in pyogenic granuloma development.
  • Early diagnosis and surgical intervention are crucial for favorable outcomes.

Keywords:
InfantIntussusceptionPregnancyProgesteronePyogenic granulomaSigmoid tumor

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