Parry Romberg Syndrome: 7 Cases and Literature Review

Area of Science:

• Neurology
• Genetics
• Dermatology

Background:

• Parry Romberg syndrome (PRS) is a rare disorder characterized by progressive hemifacial atrophy.
• It typically affects children and young adults, with onset and progression varying significantly.
• PRS diagnosis and prognosis are complicated by inconsistent atrophy patterns and associated symptoms.

Observation:

• This study presents 7 cases of Parry Romberg syndrome.
• Clinical and imaging findings were meticulously documented for each case.
• Radiographic characteristics specific to PRS were a key focus.

Findings:

• The study details the clinical presentation and imaging results of PRS patients.
• Specific radiographic features associated with hemifacial atrophy in PRS were identified.
• The variability in symptom presentation and progression was observed across the cases.

Implications:

• Understanding PRS radiographic characteristics can aid in diagnosis and management.
• Further research into PRS etiology is warranted due to its unknown cause.
• This case series contributes to the literature on Parry Romberg syndrome's diverse manifestations.