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Related Experiment Video

Updated: Apr 10, 2026

Murine Model of Wound Healing
05:39

Murine Model of Wound Healing

Published on: May 28, 2013

68.4K

Studying Wound Repair in the Mouse.

Nguan S Tan1,2, Walter Wahli3,4

  • 1School of Biological Sciences, Nanyang Technological University, Singapore.

Current Protocols in Mouse Biology
|June 13, 2015
PubMed
Summary

Animal models are essential for studying wound healing and developing new therapies. This study details reproducible methods for creating and analyzing wounds in animal models for consistent research outcomes.

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Area of Science:

  • Cutaneous wound healing research
  • Animal modeling in biomedical science
  • Regenerative medicine

Background:

  • Animal models are critical for understanding skin wound repair mechanisms.
  • Variability in healing responses necessitates standardized methodologies.
  • Developing novel wound therapies relies on robust preclinical data.

Purpose of the Study:

  • To provide standardized protocols for wound creation in animal models.
  • To outline methods for reproducible analysis of wound healing.
  • To facilitate consistent data generation for wound therapy research.

Main Methods:

  • Detailed surgical procedures for full-thickness excisional wounds.
  • Standardized techniques for incisional wounding in preclinical models.
Keywords:
IHChistologyhistomorphometricwound biopsywound modelswound repair

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Last Updated: Apr 10, 2026

Murine Model of Wound Healing
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Published on: May 28, 2013

68.4K
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  • Methods for quantitative and qualitative analysis of wound biopsies.

    • Main Results:

    • Established reproducible techniques for inducing and assessing cutaneous wounds.
    • Demonstrated the ability to characterize and quantify healing aspects consistently.
    • Provided a framework for reliable animal studies in wound repair.

    Conclusions:

    • Standardized animal models and analysis methods are key to advancing wound healing research.
    • These protocols enable reliable investigation of wound pathophysiology.
    • The described methods support the development of effective wound therapies.