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Clear cell sarcoma of the penis: a case report
Timothy Ito1, Jonathan Melamed2, Mary Ann Perle2
1Fox Chase Cancer Center Philadelphia, PA.
American Journal of Clinical and Experimental Urology
|June 13, 2015
Summary
Clear cell sarcoma of the penis is a rare cancer. This case report details a 32-year-old male with advanced penile clear cell sarcoma and rapid disease progression despite treatment.
Area of Science:
- Oncology
- Pathology
Background:
- Clear cell sarcoma of the penis is an exceptionally rare malignancy.
- Few cases have been documented in medical literature.
Observation:
- A 32-year-old male presented with an infiltrative penile neoplasm.
- The patient exhibited extensive metastatic disease to lymph nodes and bone.
Findings:
- Morphologic, immunohistochemical, and cytogenetic analyses confirmed clear cell sarcoma.
- The tumor demonstrated aggressive characteristics with rapid progression.
Implications:
- This case highlights the aggressive nature of penile clear cell sarcoma.
- Further research into effective treatments for this rare cancer is warranted.

