Related Experiment Video
Updated: Apr 10, 2026

06:08
A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
24.6K
[Endogenous Cushing's syndrome: new insights]
Timo Deutschbein1, Martin Fassnacht1
1Universitätsklinikum Würzburg, Medizinische Klinik und Poliklinik I, Schwerpunkt Endokrinologie und Diabetologie, Würzburg.
Deutsche Medizinische Wochenschrift (1946)
|June 13, 2015
Summary
Endogenous Cushing's syndrome, caused by excess cortisol, leads to significant health issues and mortality even after treatment. This review clarifies current findings to improve disease understanding.
Area of Science:
- Endocrinology
- Internal Medicine
Context:
- Endogenous Cushing's syndrome is a rare endocrine disorder characterized by excessive cortisol production.
- Patients face significant morbidity and mortality risks, persisting even after successful biochemical treatment.
Purpose:
- To review and synthesize current findings on endogenous Cushing's syndrome.
- To enhance the understanding of the disease's pathophysiology and clinical implications.
Summary:
- The manuscript consolidates recent research on endogenous Cushing's syndrome, focusing on the persistent health challenges post-treatment.
- It highlights the complex nature of the disease and its long-term effects.
Impact:
- Improved comprehension of Cushing's syndrome for clinicians and researchers.
- Potential to guide future research and improve patient management strategies for this rare endocrine condition.
Related Concept Videos
Adrenal Gland Disorders
4.1K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
4.1K
Hypothalamic-Pituitary Axis
70.9K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
70.9K
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla
3.4K
The sympathetic pathways of the collateral ganglia and adrenal medulla serve unique but interconnected roles in the sympathetic response.
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
3.4K
Abnormal Proliferation
5.4K
Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.4K

