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Risk of Intussusception After Rotavirus Vaccination: Meta-analysis of Postlicensure Studies.

Dominique Rosillon1, Hubert Buyse, Leonard R Friedland

  • 1From *GlaxoSmithKline Vaccines, Wavre, Belgium; †GlaxoSmithKline, Philadelphia, PA; and ‡Medical Research Unit on Infectious Diseases, Pediatrics Hospital, National Medical Center-Century-XXI, Mexican Institute of Social Security (IMSS), Mexico City, D.F., Mexico.

The Pediatric Infectious Disease Journal
|June 13, 2015
PubMed
Summary

Both rotavirus vaccines (RV1 and RV5) show a small increased risk of intussusception after dose 1 and dose 2. This suggests intussusception is a class effect of oral rotavirus vaccines.

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