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Published on: May 19, 2014
Measurement of Silver-π Interactions in Solution Using Molecular Torsion Balances
Josef M Maier1, Ping Li1, Jungwun Hwang1
1Department of Chemistry and Biochemistry, University of South Carolina, Columbia, South Carolina 29208, United States.
Abstract:
A new series of molecular torsion balances were designed to measure the strength of individual Ag-π interactions in solution for an Ag(I) coordinated to a pyridine nitrogen. The formation of a well-defined intramolecular Ag-π interaction in these model systems was verified by X-ray crystallography and (1)H NMR. The strength of the intramolecular Ag-π interaction in solution was found to be stabilizing in nature and quantified to be -1.34 to -2.63 kcal/mol using a double mutant cycle analysis. The Ag-π interaction was also found to be very sensitive to changes in geometry or solvent environment.
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