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Related Experiment Videos

Prenatal aneuploidy screening using cell free DNA

Dick Oepkes1, Ann Tabor2, Yuval Yaron3

  • 1Department of Obstetrics, Leiden University Medical Center, Albinusdreef 2, Leiden, 2333AA The Netherlands.

American Journal of Obstetrics and Gynecology
|June 15, 2015
PubMed
Summary

No abstract available in PubMed .

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Nondisjunction01:21

Nondisjunction

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Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
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