Related Experiment Video
Updated: Apr 10, 2026

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods
Published on: June 6, 2025
Green Chemistry Metrics with Special Reference to Green Analytical Chemistry
Marek Tobiszewski1, Mariusz Marć2, Agnieszka Gałuszka3
1Department of Analytical Chemistry, Faculty of Chemistry, Gdańsk University of Technology (GUT), 11/12 G. Narutowicza St., Gdańsk 80-233, Poland. marektobiszewski@wp.pl.
Abstract:
The concept of green chemistry is widely recognized in chemical laboratories. To properly measure an environmental impact of chemical processes, dedicated assessment tools are required. This paper summarizes the current state of knowledge in the field of development of green chemistry and green analytical chemistry metrics. The diverse methods used for evaluation of the greenness of organic synthesis, such as eco-footprint, E-Factor, EATOS, and Eco-Scale are described. Both the well-established and recently developed green analytical chemistry metrics, including NEMI labeling and analytical Eco-scale, are presented. Additionally, this paper focuses on the possibility of the use of multivariate statistics in evaluation of environmental impact of analytical procedures. All the above metrics are compared and discussed in terms of their advantages and disadvantages. The current needs and future perspectives in green chemistry metrics are also discussed.
Related Concept Videos
Development of Analytical Methods
Gravimetry: Overview
In precipitation gravimetry, the analyte is converted into a precipitate and weighed. For example, the silver content in a sample can be estimated by precipitating and...
Data Validation
Key parameters for method validation include:
Sample Preparation for Analysis: Overview
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
Gas Chromatography–Mass Spectrometry (GC–MS)
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....

