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Non-Linear Concentration-Response Relationships between Ambient Ozone and Daily Mortality
Sanghyuk Bae1, Youn-Hee Lim2, Saori Kashima3
1Public Health Medical Service, Seoul National University Hospital, Seoul, Korea; Environmental Health Center, College of Medicine, Seoul National University, Seoul, Korea.
Plos One
|June 16, 2015
Summary
Ambient ozone (O3) exposure is linked to mortality, with this study finding a non-linear relationship and specific thresholds in 13 Japanese and Korean cities. These findings suggest a critical level of ozone pollution above which mortality risks increase significantly.
Area of Science:
- Environmental Health
- Epidemiology
- Air Pollution Research
Background:
- Ambient ozone (O3) concentration is a known risk factor for mortality.
- Previous studies have debated the linearity and existence of thresholds in the O3-mortality relationship.
Purpose of the Study:
- To investigate the concentration-response relationship between ambient O3 and non-accidental mortality.
- To determine the presence and level of O3 thresholds for mortality in Japanese and Korean cities.
Main Methods:
- Poisson regression models were used, adjusting for meteorological and temporal factors.
- Linear, spline, and linear-threshold models assessed the O3-mortality association.
- Generalized additive mixed models were employed for city-combined analysis.
Main Results:
- Non-linear relationships between O3 concentration and mortality were observed in 7 out of 13 cities.
- Thresholds for O3 concentration ranged from 11 to 34 ppb across cities.
- City-combined analysis indicated a non-linear association with a threshold around 30-40 ppb.
Conclusions:
- A non-linear concentration-response relationship exists between daily mean ambient O3 and non-accidental mortality.
- Thresholds for O3 exposure were identified in Japanese and Korean urban populations.
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