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Follow-up barium study after a negative water-soluble contrast examination for suspected esophageal leak: is it
Thomas R Sanchez1, Grant S Holz2, Michael T Corwin2
1Division of Pediatric Radiology, University of California, Davis Medical Center and UC Davis Children's Hospital, 4860 Y St. Suite 3100 ACC, Sacramento, CA, 95817, USA. trsanchez@ucdavis.edu.
Insights
A follow-up barium esophogram is not valuable for diagnosing esophageal leaks when an initial water-soluble contrast esophogram is normal. Water-soluble contrast esophograms alone are highly sensitive and sufficient for diagnosis, reducing patient radiation exposure.
Area of Science:
- Radiology
- Pediatric Imaging
- Gastrointestinal Imaging
Background:
- Esophageal injuries and leaks require prompt diagnosis.
- Water-soluble contrast esophograms are often the initial imaging modality.
- The utility of a subsequent barium esophogram after a normal water-soluble study is debated.
Purpose of the Study:
- To evaluate the diagnostic value of a follow-up barium esophogram after a normal initial water-soluble contrast esophogram in pediatric patients.
- To determine if barium esophograms add diagnostic information for esophageal injury or leak detection.
Main Methods:
- Retrospective review of pediatric patients (<18 years) undergoing both water-soluble and barium esophograms.
- Analysis of diagnostic yield for esophageal injury or leak over a 9-year period (2005-2014).
- Inclusion criteria focused on patients with suspected esophageal injury due to pneumomediastinum, trauma, or foreign body ingestion.
Main Results:
- Out of 49 pediatric patients, 46 showed negative results on both esophogram types.
- Two patients had positive findings on both water-soluble and barium studies.
- One patient had a leak detected only on the water-soluble study; the barium study was normal, indicating 100% sensitivity for water-soluble contrast.
Conclusions:
- A single water-soluble contrast esophogram is highly sensitive (100%) and has a high negative predictive value for diagnosing esophageal injury or leak.
- Follow-up barium esophograms after a normal water-soluble study do not improve diagnostic accuracy.
- Routine use of follow-up barium esophograms increases study time and radiation dose without added benefit.
Abstract:
The purpose of this study was to determine the value of follow-up barium esophogram in diagnosing esophageal injury or leak if the initial water-soluble contrast examination of the esophagus is normal. An institutional review board (IRB)-approved retrospective review of all pediatric patients less than 18 years old referred to the radiology department for evaluation of esophageal injury or leak was performed for a 9-year period from 2005 to 2014. The majority of patients had unexplained pneumomediastinum, chest trauma (gunshot or puncture wound), or foreign body ingestion as the reason for the referral. Forty-nine patients (age range 10 days to 17 years) underwent an initial water-soluble esophogram immediately followed by a barium esophogram. Forty-six studies were negative on both water-soluble contrast and barium studies. Two studies were both positive on the initial water-soluble contrast and subsequent barium studies. A single study showed the esophageal leak only in the water-soluble study, with the follow-up barium exam being normal. The result of this study indicates that a single-contrast water-soluble esophogram alone is sensitive in the diagnosis of esophageal injury or leak. It has a 100 % sensitivity and negative predictive value. A follow-up barium esophogram only increases the study time and radiation dose to the patient.
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