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Spontaneous splenic rupture in a patient with congenital afibrinogenemia

Baran Cengiz Arcagök1, Nihal Özdemir1, Ayşe Tekin1

  • 1Department of Pediatrics, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.

Turk Pediatri Arsivi
|June 17, 2015
PubMed

Afibrinogenemia is a rare bleeding disorder which is observed with an incidence of 1:1 000 000. It is an autosomal recessive disease and occurs as a result of mutation in one of the three genes which code the three polypeptide chains of fibrinogen. Basic clinical findings include spontaneous bleeding, bleeding after minor trauma or due to surgery. Splenic rupture in afibrinogenemia has been reported only in 6 cases so far. In this article, we present a 15-year old congenital afibrinogenemia patient with spontaneous splenic rupture.

Keywords:
Spleen rupturebleeding disordercongenital afibrinogenemia

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