Resistance exercise induces a greater irisin response than endurance exercise
Yoshifumi Tsuchiya1, Daisuke Ando2, Kaoru Takamatsu3
1Graduate School of Sport and Health Science, Ritsumeikan University, 1-1-1, Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.
Metabolism: Clinical and Experimental
|June 18, 2015
Summary
Resistance exercise significantly boosts irisin levels more than endurance or combined exercise. This study tracked irisin concentration changes after different acute exercise types.
Area of Science:
- Exercise Physiology
- Endocrinology
- Metabolic Health
Background:
- Irisin, a myokine, plays a role in energy metabolism.
- Understanding irisin's response to exercise is crucial for metabolic health research.
- Previous studies have not fully elucidated the time-course of irisin response across different exercise modalities.
Purpose of the Study:
- To investigate the detailed time-course changes in plasma irisin concentration following acute resistance exercise (R), endurance exercise (E), and combined exercise (R+E).
- To compare the irisin response between different exercise modes.
- To explore potential correlations between irisin levels and other metabolic markers post-exercise.
Main Methods:
- Experiment 1: Assessed diurnal variation of plasma irisin in healthy males over 12 hours.
- Experiment 2: Employed a randomized crossover design with 10 healthy males performing R (8 exercises, 12 reps, 3-4 sets, 65% 1RM), E (60 min cycling at 65% VO2max), and R+E (30 min E preceded by 30 min R).
- Plasma irisin concentrations were measured over 6 hours post-exercise.
Main Results:
- No significant diurnal variation in plasma irisin was observed over 12 hours.
- Resistance exercise (R) led to a significant increase in plasma irisin 1 hour post-exercise (P<0.05).
- Neither endurance (E) nor combined (R+E) exercise showed significant irisin increases. Area under the curve (AUC) for irisin was higher in R vs. R+E (P<0.05) and correlated with blood glucose, lactate, and glycerol.
Conclusions:
- Resistance exercise elicits a superior acute irisin response compared to endurance exercise alone.
- Combined resistance and endurance exercise did not enhance irisin response beyond resistance exercise alone.
- Irisin response to exercise is mode-dependent, with resistance training showing the most pronounced effect.
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