Related Experiment Video
Updated: Apr 9, 2026
05:44
Author Spotlight: Collecting the Brain and Serum from the Same Mice Fetus to Study Brain Tumor Development
Published on: May 17, 2024
1.3K
Neurofibromatosis: part 2--clinical management
Pollyanna Barros Batista1, Eny Maria Goloni Bertollo2, Danielle de Souza Costa1
1Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Arquivos De Neuro-Psiquiatria
|June 18, 2015
Summary
Neurofibromatoses (NF) management is challenging due to varied symptoms. This guideline focuses on clinical management strategies for NF1, NF2, and schwannomatosis, aiming to improve patient quality of life.
Area of Science:
- Genetics
- Neurology
- Dermatology
Background:
- Neurofibromatoses (NF) encompass genetic disorders including NF1, NF2, and schwannomatosis.
- These conditions involve neural tumors and cutaneous manifestations, affecting a significant population.
- Advances in NF knowledge improve clinical management and patient outcomes.
Purpose of the Study:
- To provide guidelines for the clinical management of neurofibromatoses.
- To offer specific recommendations for managing neurofibromatosis type 1 (NF1).
- To address the complexities in managing NF2 and schwannomatosis (SCH).
Main Methods:
- Review of current scientific knowledge on NF.
- Development of clinical management strategies.
- Emphasis on multidisciplinary specialist support and genetic counseling.
Main Results:
- NF diagnosis is feasible for most physicians but management remains challenging.
- Wide clinical variability and unpredictable disease progression complicate patient care.
- Guidelines aim to standardize and improve NF management protocols.
Conclusions:
- Effective NF management requires a comprehensive approach involving various specialists.
- Genetic counseling is crucial, particularly for NF2 and SCH.
- Adherence to updated guidelines can enhance quality of life for NF patients.
More Related Videos
Related Concept Videos
01:24Cystic Fibrosis: Management
627
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
627
01:21Barrett Esophagus-II: Clinical Manifestations and Management
1.6K
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
1.6K
01:22Aneurysm IV: Nursing Management
598
Vigilant monitoring for aneurysm rupture is essential for patients undergoing aortic surgery.Preoperative Nursing ManagementContinuously monitor the patient for manifestations of aneurysm rupture, such as pallor, weakness, tachycardia, hypotension, abdominal, back, groin, or periumbilical pain, changes in consciousness, and a pulsating abdominal mass. Regularly assess the patient's peripheral pulses.Instruct the patient to consume a clear liquid diet the day before surgery and administer...
598
01:24Nephrotic Syndrome III : Nursing Management
477
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
477
01:28Esophageal Varices-II: Clinical Features and Management
796
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
796
01:21Inflammatory Bowel Disease V: Surgical Management
872
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
872