Related Experiment Video

Updated: Apr 9, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
05:46

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on: April 9, 2014

18.6K

Comparative Application of PLS and PCR Methods to Simultaneous Quantitative Estimation and Simultaneous Dissolution

Özgür Üstündağ, Erdal Dinç, Nurten Özdemir

    Acta Chimica Slovenica
    |June 19, 2015
    PubMed

    More Related Videos

    An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings19:57

    An Affordable HIV-1 Drug Resistance Monitoring Method for Resource Limited Settings

    Published on: March 30, 2014

    19.5K
    Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control08:37

    Development of a Quantitative Recombinase Polymerase Amplification Assay with an Internal Positive Control

    Published on: March 30, 2015

    14.9K

    Related Concept Videos

    Drug Dissolution: Requirements and Profile Comparison01:14

    Drug Dissolution: Requirements and Profile Comparison

    The acceptance criteria for dissolution profile data are anchored in Q values, representing the percentage of drug dissolved within a specified period. This assessment unfolds in three stages:First Stage: The test passes if all six drug dosage units are equal to or greater than Q plus 5%; otherwise, the sample proceeds to the second stage.Second Stage: The average of twelve units must be equal to or greater than Q, with no unit falling below Q - 15% to pass; if not, it progresses to the final...
    432
    In Vitro Drug Dissolution: Compendial Testing Models II01:09

    In Vitro Drug Dissolution: Compendial Testing Models II

    Various dissolution methods are utilized to assess a drug’s dissolution rate, including the flow-through cell, paddle-over-disk, cylinder, and reciprocating disk methods.The flow-through cell apparatus (USP (United States Pharmacopeia) method 4) comprises a reservoir for the dissolution medium and a pump that propels the medium through the cell containing the test sample. This method is crucial for assessing modified-release dosage forms with minimally soluble active ingredients,...
    596
    In Vitro Drug Dissolution: Compendial Testing Models I01:13

    In Vitro Drug Dissolution: Compendial Testing Models I

    Compendial dissolution methods are standardized procedures defined by pharmacopeias to evaluate the rate at which a drug dissolves in a specific medium. These methods ensure batch-to-batch consistency, enable quality control, and support the prediction of drug bioavailability. They are critical for both immediate and modified-release drug products.The apparatuses used for dissolution testing differ in their design and mechanical function, but all aim to simulate the physiological environment of...
    515
    In Vitro Drug Dissolution: Alternative Methods01:17

    In Vitro Drug Dissolution: Alternative Methods

    Alternative drug dissolution methods include the rotating bottle, intrinsic dissolution test, peristalsis, and the Franz diffusion cell method. The rotating bottle method involves meticulously rotating tightly capped controlled-release beads in a temperature-controlled bath. Periodic decanting of samples allows for residue assay, followed by refilling with fresh medium and testing at various pH levels to emulate the gastrointestinal tract conditions.In contrast, the intrinsic dissolution test...
    367