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Related Experiment Video

Updated: Apr 9, 2026

A Silicosis Mouse Model Established by Repeated Inhalation of Crystalline Silica Dust
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Notes from the Field: Update: Silicosis Mortality - United States, 1999-2013.

Jacek M Mazurek, Patricia L Schleiff, John M Wood

    MMWR. Morbidity and Mortality Weekly Report
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    Silicosis deaths continue despite prevention efforts, with a concerning rise in young adults. This occupational lung disease, caused by silica dust, highlights the need for continued vigilance and improved workplace safety measures.

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    Area of Science:

    • Occupational Medicine
    • Pulmonary Medicine
    • Public Health Surveillance

    Background:

    • Silicosis is a serious, preventable occupational lung disease from inhaling crystalline silica (silica).
    • It manifests in chronic, accelerated, and acute forms depending on exposure duration and concentration.
    • Recent mortality data reveal ongoing silicosis deaths, particularly among younger populations.

    Purpose of the Study:

    • To analyze national mortality data for silicosis (ICD-10 code J62) from 1999-2013.
    • To investigate occupations associated with silicosis deaths in young adults (aged 15-44 years) using 2004-2006 death certificate data.
    • To assess trends and identify concerns regarding silicosis mortality.

    Main Methods:

    • Utilized multiple cause-of-death mortality files from the National Center for Health Statistics.
    • Analyzed deaths coded as silicosis (J62) between 1999 and 2013.
    • Reviewed death certificates from 35 states (2004-2006) for decedents aged 15-44 to identify associated occupations.

    Main Results:

    • Silicosis deaths continue to occur, indicating persistent occupational risks.
    • A significant concern is the mortality from silicosis in young adults (15-44 years).
    • Twelve silicosis deaths were recorded in young adults during 2011-2013, with nine listing silicosis as the underlying cause.

    Conclusions:

    • Despite progress, silicosis remains a threat, necessitating ongoing prevention strategies.
    • Silicosis deaths in young adults suggest intense exposures leading to rapid disease progression.
    • Further research into high-exposure occupations and targeted interventions is crucial for preventing silicosis mortality.