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Electroosmotic flow rectification in conical nanopores.

Nadanai Laohakunakorn, Ulrich F Keyser

|June 19, 2015

Summary

Electroosmotic flows (EOFs) in conical nanopores show inverse rectification compared to ionic current. Simulations reveal that concentration polarization, driven by pore asymmetry and permselectivity, causes this unique behavior.

Area of Science:

Nanofluidics
Electrokinetics
Computational Physics

Background:

Experimental studies indicate anomalous electroosmotic flow (EOF) rectification in conical nanopores.
This EOF rectification is opposite to the typical ionic current rectification observed in similar systems.

Purpose of the Study:

To systematically investigate the inverse rectification of EOF in conical nanopores.
To elucidate the underlying physical mechanisms responsible for this phenomenon using computational simulations.

Main Methods:

Finite-element simulations were employed to model EOF and ionic current.
Analysis focused on the interplay between electric fields and salt concentrations within the nanopore.

Main Results:

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A strong inverse correlation between electric field and salt concentration was identified inside the pore.
This inverse correlation leads to larger EOF under positive bias and larger current under negative bias.
Concentration polarization was confirmed as the key mechanism driving the observed rectification.

Conclusions:

The inverse rectification of EOF in conical nanopores is governed by concentration polarization.
Pore permselectivity and asymmetry are essential prerequisites for this effect.
Understanding this phenomenon is crucial for designing nanopore-based devices with tailored transport properties.