Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Protein-Protein Interfaces

Protein-Protein Interfaces

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

PDBe-SIFTS: an open-source tool for Structure Integration with Function, Taxonomy, and Sequences, featuring improved alignment, scoring scheme, and accelerated search.

bioRxiv : the preprint server for biology·2026

Same author

Advances in Protein Function Prediction from the Fifth CAFA Challenge.

bioRxiv : the preprint server for biology·2026

Same author

Expanding the human proteome with microproteins and peptideins.

Nature·2026

Same author

Upcycling pyrolyzed biowaste into functional alkali-activated biochar for hydrogen sulphide capture.

Waste management & research : the journal of the International Solid Wastes and Public Cleansing Association, ISWA·2026

Same author

An AI-Ready Phosphorylation Meta-Analysis for <i>Saccharomyces cerevisiae</i>.

Journal of proteome research·2026

Same author

A Landscape Analysis of Human SUMOylation.

Molecular & cellular proteomics : MCP·2026

Same journal

Protein Sequence Analysis Using the MPI Bioinformatics Toolkit.

Current protocols in bioinformatics·2020

Same journal

Exploring Manually Curated Annotations of Intrinsically Disordered Proteins with DisProt.

Current protocols in bioinformatics·2020

Same journal

Network Building with the Cytoscape BioGateway App Explained in Five Use Cases.

Current protocols in bioinformatics·2020

Same journal

Expanding the Perseus Software for Omics Data Analysis With Custom Plugins.

Current protocols in bioinformatics·2020

Same journal

Exploring Non-Coding RNAs in RNAcentral.

Current protocols in bioinformatics·2020

Same journal

How to Illuminate the Dark Proteome Using the Multi-omic OpenProt Resource.

Current protocols in bioinformatics·2020

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 9, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Searching and Navigating UniProt Databases.

Sangya Pundir¹, Michele Magrane¹, Maria J Martin¹

¹European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, United Kingdom.

Current Protocols in Bioinformatics

|June 20, 2015

Summary

This summary is machine-generated.

This paper guides users on effectively navigating and searching the Universal Protein Resource (UniProt) datasets. It details basic and advanced methods for accessing comprehensive protein sequence and annotation data.

Keywords:

UniProt navigation search tutorial

More Related Videos

An Integrated Approach for Microprotein Identification and Sequence Analysis

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

Related Experiment Videos

Last Updated: Apr 9, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

An Integrated Approach for Microprotein Identification and Sequence Analysis

An Integrated Approach for Microprotein Identification and Sequence Analysis

Published on: July 12, 2022

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Investigating Protein Sequence-structure-dynamics Relationships with Bio3D-web

Published on: July 16, 2017

Area of Science:

Bioinformatics
Molecular Biology
Genomics

Background:

The Universal Protein Resource (UniProt) is a critical global data repository for protein sequences and functional annotations.
The UniProt website serves as the primary access point, attracting approximately 400,000 unique visitors monthly.
UniProt offers ten searchable datasets and three main tools for protein data retrieval.

Purpose of the Study:

To provide a practical guide on utilizing the diverse datasets within the Universal Protein Resource (UniProt).
To explain the navigation and searching functionalities of UniProt datasets for researchers.
To demonstrate advanced search and query-building techniques for efficient data retrieval.

Main Methods:

The paper outlines a basic protocol for navigating and searching UniProt datasets.
Two alternative protocols are presented to cover advanced search strategies and complex query construction.
The focus is on practical application and user guidance for accessing protein information.

Main Results:

Users can learn to effectively search and retrieve specific protein data from UniProt.
The protocols enable users to move from basic data discovery to sophisticated query building.
Understanding these methods enhances the utility of UniProt for research purposes.

Conclusions:

The Universal Protein Resource (UniProt) provides essential protein data through various accessible datasets.
This guide empowers researchers to maximize their use of UniProt through effective search strategies.
Mastering UniProt dataset usage is crucial for advancing research in protein science and related fields.