Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Computed Tomography01:10

Computed Tomography

9.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
9.6K
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

3.1K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
3.1K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

740
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
740
Positron Emission Tomography01:29

Positron Emission Tomography

8.1K
Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
8.1K
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.4K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.4K
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

1.2K
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluating a maternal and child health capacity-building program in Senegal: environment-adjusted district efficiency and gap reduction using DHIS2 data.

BMC health services research·2026
Same author

STARE: a semiconductor-integrated transmit-array architecture for 6G beamforming.

Nature communications·2026
Same author

Operando Electrochemical Formation of Integrated Ni-Fe Oxyhydroxide Anode for Durable Anion Exchange Membrane Water Electrolyzer.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

A Fungal-Derived Bioactive Resource for Cochlear Protection: <i>Sanghuangporus sanghuang</i> Extract Mitigates Acoustic Trauma through Nrf2/HO-1 Antioxidant Axis.

Journal of microbiology and biotechnology·2026
Same author

Infectious complications after CAR T-cell therapy: mechanisms, risk stratification, and prevention.

Blood research·2026
Same author

Food literacy as a moderator in the relationship between food security and dietary diversity among adults in Seoul: based on the 2021-2023 Seoul Food Survey.

Nutrition research and practice·2026

Related Experiment Video

Updated: Apr 9, 2026

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy
09:47

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

Published on: July 15, 2021

5.6K

From a meso- to micro-scale connectome: array tomography and mGRASP.

Jong-Cheol Rah1, Linqing Feng2, Shaul Druckmann3

  • 1Korea Brain Research Institute Daegu, South Korea ; Department of Brain Science, Daegu Gyeongbuk Institute of Science and Technology (DGIST) Daegu, South Korea.

Frontiers in Neuroanatomy
|June 20, 2015
PubMed
Summary

Advanced microscopy techniques like Array Tomography (AT) and mammalian GFP-Reconstitution Across Synaptic Partners (mGRASP) enable high-throughput mapping of mammalian brain connectivity at multiple scales, crucial for understanding brain function.

Keywords:
3D atlasingarray tomographyconnectomemGRASPmultiple scales

More Related Videos

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography
11:33

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Published on: January 30, 2016

11.5K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.6K

Related Experiment Videos

Last Updated: Apr 9, 2026

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy
09:47

Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy

Published on: July 15, 2021

5.6K
Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography
11:33

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

Published on: January 30, 2016

11.5K
Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.6K

Area of Science:

  • Neuroscience
  • Connectomics
  • Microscopy

Background:

  • Mapping synaptic connectivity is essential for understanding brain function.
  • Existing techniques lack the resolution and scale needed for comprehensive connectome mapping.
  • Bridging the meso- and micro-scale connectome requires advanced tools.

Purpose of the Study:

  • To discuss advanced light microscopy (LM)-based tools for mapping mammalian brain circuits.
  • To highlight the utility of Array Tomography (AT) and mammalian GFP-Reconstitution Across Synaptic Partners (mGRASP).
  • To explore the functional implications of synaptic distribution and future challenges.

Main Methods:

  • Array Tomography (AT) for high-throughput synaptic mapping.
  • Mammalian GFP-Reconstitution Across Synaptic Partners (mGRASP) for circuit tracing.
  • Integration with retrograde viruses, brain clearing, and activity indicators.

Main Results:

  • AT and mGRASP provide high-throughput synaptic connectivity mapping at multiple scales.
  • These methods, combined with other techniques, facilitate detailed circuit analysis.
  • The spatial distribution of synapses has functional implications.

Conclusions:

  • Advanced tools like AT and mGRASP are unlocking secrets of complex neural circuits.
  • Mapping brain circuits at multiple scales is becoming increasingly feasible.
  • Future research directions involve refining these techniques and exploring functional insights.