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Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
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Imaging agents based on lanthanide doped nanoparticles
L Prodi1, E Rampazzo, F Rastrelli
1Dipartimento di Chimica "G. Ciamician" and INSTM, UdR Bologna, Università di Bologna, Via Selmi 2, 40126 Bologna, Italy. luca.prodi@unibo.it.
Chemical Society Reviews
|June 20, 2015
Summary
Lanthanide-based nanocrystals offer bright upconversion light for advanced applications. These nanoparticles show promise as multimodal imaging agents, especially for in vivo studies using near-infrared emission.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Imaging
Background:
- Nanoparticles are versatile platforms addressing complex scientific challenges.
- Lanthanide-based nanocrystals exhibit unique light-emitting properties, including upconversion.
Purpose of the Study:
- To survey recent advancements in lanthanide-based nanocrystals.
- To highlight their potential as multimodal imaging agents for in vivo applications.
Main Methods:
- Focus on nanoparticles derived from lanthanide materials.
- Exploration of near-infrared-to-near-infrared (NIR-to-NIR) emission properties.
Main Results:
- Lanthanide nanocrystals demonstrate high brightness upconversion emission.
- Emerging advantageous characteristics are noted for various applications.
Conclusions:
- Lanthanide-based nanocrystals are promising for advanced imaging.
- NIR-to-NIR emitting systems are particularly relevant for in vivo applications.
