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Updated: Aug 11, 2026

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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Epidemiology of multiple sclerosis in Romania
Summary
This study determined the prevalence and incidence of multiple sclerosis (MS) in 34 countries, finding a mean prevalence rate of 25.7% and an incidence rate of 1.78% between 1980-1984. Combined data increased the overall prevalence to 30%.
Area of Science:
- Neurology
- Epidemiology
Background:
- Multiple Sclerosis (MS) is a chronic neurological disease.
- Understanding the geographical distribution and incidence of MS is crucial for public health planning.
Purpose of the Study:
- To determine the prevalence and incidence rates of Multiple Sclerosis (MS) in a large population across 34 countries.
- To update MS prevalence figures by incorporating historical data.
Main Methods:
- Data collection from 34 countries, representing 76.17% of the national population.
- Involved analysis of 4424 definite MS cases, with demographic data including sex and age.
- Prevalence calculated on a specific day (July 1, 1984), with incidence estimated for 1980-1984.
Main Results:
- The mean prevalence rate of MS was established at 25.7% of the population.
- The mean incidence rate for the period 1980-1984 was 1.78%.
- Incorporating data from Bucharest and a county study, the overall prevalence was modified to 30%.
Conclusions:
- The study provides significant epidemiological data on MS prevalence and incidence.
- The findings highlight the public health burden of MS in the studied regions.
- Updated prevalence figures offer a more comprehensive understanding of MS distribution.
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