Related Experiment Video
Updated: Apr 9, 2026
09:00
TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
Published on: April 13, 2021
5.6K
[Lazio dialysis registry: natives vs foreigners]
Summary
Foreign-born patients on chronic dialysis in Lazio show increased prevalence and better survival rates compared to Italians. Younger age likely explains demographic differences, but further research is needed.
Area of Science:
- Nephrology
- Public Health
- Epidemiology
Background:
- Increasing prevalence of foreign patients undergoing chronic dialysis in Italy.
- Need to compare demographic, clinical, treatment, and survival characteristics between Italian and foreign dialysis patients in Lazio.
Purpose of the Study:
- To compare demographic, clinical, treatment, and survival outcomes of Italian and foreign chronic dialysis patients in Lazio.
- To investigate mortality risk differences between these groups.
Main Methods:
- Analysis of data from the Lazio Dialysis and Transplantation Registry (2004-2012).
- Inclusion of 4,076 prevalent and 7,970 incident chronic dialysis patients.
- Survival probability assessed using Kaplan-Meier method; mortality risk evaluated via multiple Cox regression.
Main Results:
- Foreign dialysis patient proportion increased from 4.4% to 7.6% (p<0.001) between 2004 and 2012.
- Foreign patients were younger, more often women, HbsAg-positive, unvaccinated for HBV, with late referral, and more suitable for transplantation.
- Foreigners exhibited higher 1-year (91.9% vs. 84.7%) and 5-year (74.6% vs. 51.5%) survival rates and lower mortality risk (HR=0.71).
Conclusions:
- Foreign dialysis patients in Lazio demonstrate superior survival probabilities compared to Italians.
- Demographic differences, particularly younger age, likely contribute to observed variations.
- Health status and end-stage renal disease treatment, including kidney transplantation access, appear comparable, warranting further investigation into survival disparities.
Related Concept Videos
01:15Dialysis
2.2K
Dialysis is a diffusion-based purification process that separates analyte molecules from a complex matrix. This is accomplished by allowing molecules in the solution to pass through a semipermeable membrane into a liquid on the other side. The membrane is usually made of cellulose acetate or cellulose nitrate, and the second liquid must be miscible with the solution. Ions (e.g., chloride or sodium) or organic molecules (e.g., glucose) can pass through the membrane pores, which generally have...
2.2K
01:27Dialysis
2.0K
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
2.0K
01:25Hemodialysis I: Introduction
3.4K
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
3.4K
01:24Hemodialysis II: Procedure and Complications
1.9K
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
1.9K
01:30Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
916
Patients with end-stage renal disease (ESRD) or those experiencing drug overdose often require extracorporeal methods to eliminate accumulated drugs and metabolites. Hemoperfusion, hemofiltration, and dialysis are the primary techniques to rapidly remove harmful substances without disrupting the patient's fluid and electrolyte balance. For those with compromised renal function, dosage adjustments of concurrent medications may be necessary during extracorporeal drug removal.Dialysis is a process...
916
01:28Kidney Transplant I: Introduction
724
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
724