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Demyelinating neuropathy in genetically confirmed acute intermittent porphyria

David S Younger1, Kurenai Tanji2

  • 1Department of Neurology, New York University School of Medicine, and the Global Institute of Public Health, New York University, New York.

Muscle & Nerve
|June 23, 2015
PubMed
Abstract

No abstract available in PubMed .

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Phase II biotransformation reactions are essential for detoxifying and eliminating xenobiotics, including many pharmaceutical compounds. These reactions typically involve conjugation, the covalent attachment of polar endogenous groups such as glucuronic acid, sulfate, methyl, or acetyl moieties to functional groups introduced during Phase I metabolism. The resulting conjugates are more water-soluble, enabling efficient renal or biliary excretion.The major classes of Phase II enzymes include...
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