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Trends in celiac disease research.
Edward J Ciaccio1, Govind Bhagat2, Suzanne K Lewis1
1Department of Medicine - Celiac Disease Center, Columbia University, New York, USA.
Computers in Biology and Medicine
|June 23, 2015
Summary
Research on celiac disease (CD) shows increasing focus on diagnosis, gluten, autoimmune aspects, and microbiome. This analysis helps plan future research directions for CD and compare trends with inflammatory bowel disease (IBD).
Area of Science:
- Biomedical research trends
- Bibliometrics
- Medical informatics
Background:
- Celiac disease (CD) diagnosis and treatment research requires strategic planning.
- Understanding research focus and trends is crucial for future efforts.
Observation:
- A MEDLINE search analyzed CD research trends from 1960 to 2013.
- Keywords associated with CD were tracked, alongside comparisons with inflammatory bowel disease (IBD).
Findings:
- Keywords like 'diagnosis,' 'gluten,' 'autoimmune,' 'treatment,' 'inflammation,' and 'microbiome' show strong positive trends with CD.
- Research on CD surpassed IBD in publication volume starting in 1988.
- 'Malabsorption' showed a negative trend in association with CD.
Implications:
- The study provides a clear overview of CD research focus and evolution.
- This bibliometric analysis aids in planning future research directions for celiac disease.
- Comparing CD research trends with IBD offers valuable insights into disease-specific research trajectories.
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