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Related Concept Videos

Cytoskeletal Linker Proteins - Plakins01:09

Cytoskeletal Linker Proteins - Plakins

Plakins are large proteins with binding domains for microtubules, microfilaments, intermediate filaments, and membrane-associated protein complexes at cell junctions. Plakin functions are evolutionarily conserved and are primarily involved in organizing the different components of the cytoskeleton by crosslinking them to each other and connecting them to the cell-matrix and cell adhesion complexes. They are also known to interact with signal transducers, serve as scaffolds for signaling...
Desmosomes01:05

Desmosomes

The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

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Same author

[Lipids peroxidation in children with atopic dermatitis].

Pediatriia·1991
Same author

[Experience with the study of disorders of porphyrin metabolism].

Laboratornoe delo·1990
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[The diagnostic importance of research on the lysyl oxidase activity in children with circumscribed scleroderma].

Vestnik dermatologii i venerologii·1990
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[The immunomodulating action of interferon. The change in the rosette-forming activity of human blood lymphocytes under the influence of gamma-interferon and recombinant alpha 2-interferon].

Vestnik dermatologii i venerologii·1990
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[Devergie's lichen ruber pilaris].

Vestnik dermatologii i venerologii·1990
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[A case of combined multiple leiomyomas of the skin and psoriasis].

Vestnik dermatologii i venerologii·1990

Related Experiment Video

Updated: Jun 30, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

[The plaque form of polymorphous photodermatosis].

V G Akimov, M N Sheklakova, M O Olisova

    Vestnik Dermatologii I Venerologii
    |January 1, 1989
    PubMed
    Summary

    This study describes two patients with plaque photodermatosis. Researchers propose

    Area of Science:

    • Dermatology
    • Photobiology

    Background:

    • Photodermatoses encompass a range of skin conditions triggered by sunlight.
    • Understanding the classification and clinical presentation of photodermatoses is crucial for accurate diagnosis.

    Observation:

    • Two cases of the plaque form of photodermatosis were observed.
    • Clinical features resembled discoid lupus erythematosus but differed from prurigo or eczema.

    Findings:

    • The plaque form of photodermatosis shares similarities with discoid lupus erythematosus.
    • Observed manifestations suggest a spectrum of disease rather than distinct entities.

    Implications:

    • The term 'polymorphic photodermatosis' is proposed to encompass variants like solar prurigo and solar eczema.

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  • This unified terminology may improve diagnostic clarity and patient management for light-induced skin conditions.