[alpha-Tocopherol in the combined treatment of vitiligo]

Photochemotherapy was combined with alpha-tocopherol in the treatment of 56 patients with vitiligo in order to shorten the treatment. alpha-tocopherol was used as antioxidant to reduce skin erythema and build up single UV doses. Due to 1.5-2-fold increase of UV exposure follicular mechanisms stimulation was enhanced in vitiligo foci, perifollicular pigmentation was achieved approximately 2 times sooner, and the length of treatment necessary to achieve manifest repigmentation (i.e. more than 50% of the maculae surface) was reduced twofold.