Related Experiment Video
Updated: Aug 12, 2026

Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
[Pemphigus herpetiformis]
Abstract:
A female patient aged 68 has developed polycyclically shaped erythematous plaques with herpetiform vesicles, bullae, and crusts, intensively itching. Histologic analysis has revealed bullae with acantholytic cells and eosinophils. Eosinophils were present in the epidermis as well as in the derma. Both the direct and indirect immunofluorescence tests detected intercellular IgG. These findings have lead the authors to a conclusion that the present case was an atypical form of pemphigus, pemphigus herpetiformis. The disease regressed rather soon after treatment with moderate doses of corticosteroids.
Related Concept Videos
Desmosomes
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
Peptic Ulcer
Gastritis II: Pathophysiology
Peptic Ulcer Disease II: Pathophysiology

