Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

827
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
827
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

593
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
593
Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

435
Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
435
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

86.9K
Overview
86.9K
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

581
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
581
Inflammatory Response01:28

Inflammatory Response

19.3K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
19.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Creation and Evaluation of a Research Participant Portal for the University of Chicago Monogenic Diabetes Registry.

Journal of diabetes science and technology·2025
Same author

Epidemiology of Community-Acquired Versus Hospital-Acquired Sepsis in Acute Hospitals in Ireland, 2016-2022.

Critical care explorations·2025
Same author

A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.

Annals of surgery·2023
Same author

Epidemiology and Survival of Dogs Diagnosed with Splenic Lymphoid Hyperplasia, Complex Hyperplasia, Stromal Sarcoma and Histiocytic Sarcoma.

Animals : an open access journal from MDPI·2022
Same author

Theriogenology Question of the Month.

Journal of the American Veterinary Medical Association·2020
Same author

Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery.

PloS one·2018
Same journal

Cardiogenic shock - toward phenotype-directed, precision management.

Current opinion in critical care·2026
Same journal

The future of critical care nutrition: from calorie counting to precision personalized metabolism therapy.

Current opinion in critical care·2026
Same journal

Editorial introduction.

Current opinion in critical care·2026
Same journal

Generative artificial intelligence for outcome prediction in critical care: the future is now?

Current opinion in critical care·2026
Same journal

Feeding under support in critical care illness: metabolic and nutritional management during extracorporeal membrane oxygenation and continuous renal replacement therapy.

Current opinion in critical care·2026
Same journal

Multinational collaborations in critical care research: feasible and useful?

Current opinion in critical care·2026
See all related articles

Related Experiment Video

Updated: Apr 8, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

30.7K

The perioperative immune response.

Michael J O'Dwyer1, Helen C Owen, Hew D T Torrance

  • 1aCentre for Translational Medicine and Therapeutics, William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London bAdult Critical Care Unit, Royal London Hospital, Barts Health NHS Trust cCentre for Trauma Sciences, Blizard Institute, Barts and the London School of Medicine, Queen Mary University of London, London, United Kingdom.

Current Opinion in Critical Care
|June 24, 2015
PubMed
Summary
This summary is machine-generated.

Understanding perioperative immune responses is crucial. Novel monitoring techniques and analysis of anesthetic effects can personalize patient care and improve outcomes, reducing risks like infection and organ failure.

More Related Videos

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

1.6K
Cecal Ligation Puncture Procedure
11:53

Cecal Ligation Puncture Procedure

Published on: May 7, 2011

56.6K

Related Experiment Videos

Last Updated: Apr 8, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
13:37

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

30.7K
Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

1.6K
Cecal Ligation Puncture Procedure
11:53

Cecal Ligation Puncture Procedure

Published on: May 7, 2011

56.6K

Area of Science:

  • Immunology
  • Anesthesiology
  • Translational Medicine

Background:

  • The perioperative period significantly alters host immunity, potentially leading to adverse outcomes such as infection, cancer recurrence, and organ failure.
  • Immune modulation during this critical window offers a potential strategy to improve patient outcomes.
  • A comprehensive understanding of perioperative immune alterations is essential for clinical advancement.

Purpose of the Study:

  • To review the current understanding of immune modulation in the perioperative setting.
  • To highlight the impact of perioperative immune alterations on clinical outcomes.
  • To emphasize the potential for manipulating the immune response to improve patient care.

Main Methods:

  • Utilizing novel laboratory techniques to monitor single-cell immune signatures in vivo.
  • Applying traditional gene expression assays to define host responses, such as to perioperative allogeneic blood transfusion.
  • Analyzing large clinical studies to identify associations between anesthetic modalities and immune-related outcomes.

Main Results:

  • Emerging in vivo data elucidate the interplay between tissue damage, immune modulation, and clinical outcomes.
  • Gene expression assays have proven effective in characterizing host responses to perioperative interventions.
  • Clinical studies reveal links between anesthetic approaches and subsequent immune-related events.

Conclusions:

  • Advanced laboratory techniques enable perioperative immune response monitoring, paving the way for personalized medicine.
  • Anesthetic techniques and perioperative treatments can induce immunosuppression, potentially causing delayed adverse outcomes.
  • Further research into perioperative immune modulation is imperative for optimizing patient management and reducing long-term complications.