Related Experiment Video
Updated: Apr 8, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
PP031. The prevalence of microalbuminuria following preeclampsia
J Spaan1, L Peeters2, M Spaanderman1
1Obstetrics and Gynecology, Maastricht University Medical Center, Maastricht, The Netherlands.
Introduction:
About 7years after preeclampsia, the prevalence of microalbuminuria is reported to be around 30% [1]. As proteinuria resolves in most cases within two years of post partum, [2] this raises the question of whether microalbuminuria first regresses after preeclampsia or persists.
Objectives:
This cross-sectional study describes the prevalence of microalbuminuria in the years following preeclampsia.
Methods:
Women with a history of preeclampsia (n=823) were evaluated 4-180months after delivery. Women with pre-existing hypertension, renal disease or diabetes mellitus were excluded (n=65). In a 24h urine collection we determined total protein (pyrogallol red), microalbuminuria (turbidometry, Cobas Bio and since 2007 nephelometry, BN ProSpec) and creatinine (Jaffe method). Microalbuminuria was considered to be present when there was ⩾3.5mg/mmol of creatinine. Proteinuria was defined as a total protein level of ⩾300mg/24h.
Results:
Microalbuminuria was present in 12.0%, CI 9.7-14.6 and proteinuria in 2.7%, CI 1.7-4.1 of all cases. Microalbuminuria decreased up to 40months postpartum, but increased after that period of time (p=0.01 compared with 24-40months).
Conclusion:
This study suggests a U-shaped microalbuminuria pattern over time. Longitudinal research is necessary to confirm this.
More Related Videos
11:47Using 2-Photon Microscopy to Quantify the Effects of Chronic Unilateral Ureteral Obstruction on Glomerular Processes
Published on: March 4, 2022
11:13Quantifying Glomerular Permeability of Fluorescent Macromolecules Using 2-Photon Microscopy in Munich Wistar Rats
Published on: April 17, 2013
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Nephrotic Syndrome I : Introduction
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Diabetes Mellitus: Type 2 and Gestational
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Nephrotic Syndrome III : Nursing Management