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PP100. Pre-eclampsia: Risk factors and outcomes - A two-year study.
A V Santos1, F Caeiro1, G Dias1
1Obstetrics and Gynecology, Hospital Fernando Fonseca, Varzea de Sintra, Lisbon, Portugal.
Pre-eclampsia (PE) is a serious pregnancy disorder. Key risk factors include prior PE, advanced maternal age, and chronic hypertension, often leading to preterm delivery and maternal complications.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Hypertensive Disorders of Pregnancy
Background:
- Pre-eclampsia (PE) is a significant cause of maternal and fetal morbidity and mortality.
- Predicting PE remains a clinical challenge despite known risk factors.
Purpose of the Study:
- To determine the incidence of pre-eclampsia.
- To identify associated risk factors for PE.
- To evaluate maternal and fetal outcomes in PE cases.
Main Methods:
- Retrospective review of clinical records for pregnant women diagnosed with pre-eclampsia.
- Data collected from January 2008 to December 2009 at Prof. Fernando Fonseca's Hospital.
- Statistical analysis performed using Excel 2007.
Main Results:
- PE occurred in 1.1% of pregnant women (90 cases out of 308 hypertensive disorders).
- Associated risk factors included chronic hypertension (24.4%), maternal age >35 (16.67%), age <20 (14.44%), and prior PE (8.89%).
- Maternal complications led to ICU admission in 18.89% of cases, including 3.33% with HELLP syndrome; 61.1% experienced preterm delivery.
Conclusions:
- Pre-eclampsia is a recurrent hypertensive disorder with severe potential, often linked to preterm delivery and significant maternal morbidity.
- Confirmed adverse outcomes include ICU admissions, HELLP syndrome, and end-organ failure.
- Identified risk factors reinforce the need for vigilant monitoring and management in high-risk pregnancies.
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