PP067. Third trimester prediction of late PE

Area of Science:

• Obstetrics and Gynecology
• Maternal-Fetal Medicine
• Pregnancy Complications

Background:

• First and second-trimester models predict early preeclampsia (PE) but are less accurate for late PE.
• Different physiopathologies are suggested for early versus late PE.
• Third-trimester screening is a novel approach for late PE prediction.

Purpose of the Study:

• To evaluate the predictive capacity of maternal characteristics measured during the third trimester for late-onset PE.

Main Methods:

• A cross-sectional study included 4724 pregnancies.
• Maternal characteristics (mean arterial pressure, body mass index, weight gain, parity, age) were recorded at the 3rd trimester visit (31-33 weeks).
• Multivariate logistic regression analysis identified independent predictors of late PE.

Main Results:

• Late PE occurred in 1.2% of pregnancies.
• Mean arterial pressure and body mass index were significant, independent predictors of late PE.
• A model combining BMI and MAP achieved an AUC of 0.76 for predicting late PE.

Conclusions:

• Third-trimester screening using maternal characteristics shows potential for predicting late-onset PE.
• This approach may improve the management of late PE.
• Further research can refine third-trimester screening protocols.