Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

7.5K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
7.5K
Accessory Structures of the Eye01:17

Accessory Structures of the Eye

4.5K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
4.5K
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

11.2K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
11.2K
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.7K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Serum magnesium in diabetic retinopathy: the association needs investigation.

Therapeutic advances in ophthalmology·2021
Same author

Maxillofacial trauma and ocular injuries: reports from a prospective study from Pondicherry, India.

Orbit (Amsterdam, Netherlands)·2021
Same author

Comparison of Central Corneal Thickness using Anterior Segment Optical Coherence Tomography Versus Ultrasound Pachymetry.

Journal of clinical and diagnostic research : JCDR·2017
Same author

Multimodal Hallucinations in a Visually Impaired Elderly Female: Is it a Variant of Charles Bonnet Syndrome?

Indian journal of psychological medicine·2017
Same author

Indian Soldiers Need Eye Protection.

Journal of clinical and diagnostic research : JCDR·2017
Same author

Role of Optical Coherence Tomography in Assessing Anterior Chamber Angles.

Journal of clinical and diagnostic research : JCDR·2016
Same journal

Benchmarking and fine-tuning vision-language models on a visual question answering dataset for myopic maculopathy.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
Same journal

Does lens opacity matter? The effect of cataract on deep learning based cardiovascular disease risk scores from fundus photos.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
Same journal

Corrigendum to "Oculomics and AI: The eye as a biomarker for health span" [Asia-Pac J Ophthalmol 15 (1) (2026) 100282].

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
Same journal

Visual preservation and surgical outcomes of phacogoniotomy in end-stage glaucoma: A multicenter study.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
Same journal

Association of asymmetrical normal tension glaucoma, obstructive sleep apnoea and side sleeping.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
Same journal

Mechanism of myopic axial elongation related to Bruch´s membrane.

Asia-Pacific journal of ophthalmology (Philadelphia, Pa.)·2026
See all related articles

Related Experiment Video

Updated: Apr 8, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

10.5K

High Altitude and the Eye.

Kirti Nath Jha1

  • 1From the Department of Ophthalmology, Manipal College of Medical Sciences and Manipal Teaching Hospital, Pokhara, Nepal.

Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.)
|June 25, 2015
PubMed
Summary
This summary is machine-generated.

High altitude affects the eyes, causing short-term issues like retinopathy and long-term problems such as cataracts. Understanding these ocular effects is crucial for eye health at elevation.

More Related Videos

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
07:00

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

13.7K
Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method
09:11

Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method

Published on: October 27, 2020

6.3K

Related Experiment Videos

Last Updated: Apr 8, 2026

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
09:03

Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye

Published on: June 20, 2015

10.5K
A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects
07:00

A Laser-induced Mouse Model of Chronic Ocular Hypertension to Characterize Visual Defects

Published on: August 14, 2013

13.7K
Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method
09:11

Assessment of Global Ocular Structure Following Spaceflight Using a Micro-Computed Tomography Micro-CT Imaging Method

Published on: October 27, 2020

6.3K

Area of Science:

  • Ophthalmology
  • Altitude Medicine
  • Environmental Health

Background:

  • High altitude environments present unique physiological challenges.
  • Ocular health can be significantly impacted by reduced oxygen and increased UV radiation at high altitudes.

Purpose of the Study:

  • To comprehensively review existing literature on the ocular effects of high altitude.
  • To identify both short-term and long-term impacts on various eye structures and functions.

Main Methods:

  • Conducted an electronic literature search of PubMed up to 2011.
  • Utilized search terms related to high altitude, eye conditions, and specific ocular functions.
  • Included prospective and retrospective English-language studies.

Main Results:

  • Short-term effects include high-altitude retinopathy, altered corneal thickness, and photokeratitis.
  • Long-term effects encompass pterygium, cataract development, and dry eye syndrome.
  • Mild retinopathy can predict cerebral edema; corneal changes affect refractive surgery outcomes; scotopic vision may decrease without supplemental oxygen.

Conclusions:

  • High altitude induces a range of ocular changes, from retinopathy to dry eye.
  • Awareness of these effects is vital for managing eye health in high-altitude populations.
  • Further research may be needed to fully elucidate long-term impacts and mitigation strategies.