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Global Prevalence of Small for Gestational Age Births
1Institute for International Programs, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Insights
Millions of babies are born small for gestational age (SGA), especially in South Asia and Africa. This condition significantly impacts infant health and development, necessitating better assessment using gestational age and birthweight data.
Area of Science:
- Perinatal Medicine
- Global Child Health
- Developmental Pediatrics
Background:
- Fetal growth restriction, impacting preterm and full-term infants, leads to adverse outcomes in survival, health, growth, and development.
- Small for gestational age (SGA) is defined as a newborn's weight below the 10th percentile for their gestational age.
- SGA prevalence is notably higher than low-birthweight (<2,500g) births globally.
Purpose of the Study:
- To estimate the global burden of SGA births in low- and middle-income countries.
- To highlight regional disparities in SGA prevalence.
- To emphasize the importance of using gestational age alongside birthweight for accurate newborn risk assessment.
Main Methods:
- Estimation of SGA births based on available data for low- and middle-income countries in 2010.
- Comparison of SGA prevalence with low-birthweight prevalence.
- Analysis of regional distribution of SGA births.
Main Results:
- In 2010, an estimated 32.4 million babies were born SGA in low- and middle-income countries, representing 27% of all live births.
- The highest prevalence of SGA is observed in South Asia and Sahelian Africa.
- India reported the largest number of SGA births (12.8 million in 2010).
Conclusions:
- SGA births present a significant global health challenge, particularly in South Asia and Africa.
- The prevalence of SGA is substantially higher than previously indicated by low-birthweight data alone.
- Maternal, neonatal, and child health programs must integrate gestational age assessment with birthweight to effectively manage SGA risks.
Abstract:
Fetal growth restriction is found both in babies who are preterm or full-term, and in either case has important adverse effects on subsequent survival, health, growth and development. Fetal growth restriction is usually assessed by comparing the weight of the newborn with the expected weight for the child's gestational age using less than the 10th centile of a reference population for fetal growth as the threshold for being called small for gestational age (SGA). We estimate that in 2010 32.4 million babies were born SGA in low- and middle-income countries, constituting 27% of all live births. The estimated prevalence of SGA is highest in South Asia and in Sahelian countries of Africa. India has the world's largest number of SGA births, 12.8 million in 2010, due to the large number of births and the high proportion, 46.9%, of births that are SGA. The prevalence of SGA births is approximately double the prevalence of low-birthweight births (using the common indicator of <2,500 g birthweight) globally and in the world's regions. Thus, given the adverse effects of being born SGA, even weighing 2,500 g or more, it is important that maternal, neonatal and child health programs seek and use information on gestational age as well as birthweight to appropriately assess the newborn's risks and direct care.
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